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SBML Discussions » sbml-discuss » RE: A model representation in SBML in which the enzyme represented as a Modifier
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Herbert Sauro


Posts: 349
Registered:
September 2003
RE: A model representation in SBML in which the enzyme represented as a Modifier 27 Dec '04 11:26


I think it depends how to you express the enzyme in the rate law,
consider the two examples below:

v = Vmax * S / (Km + S)

Is the Vmax a modifier or a parameter, I think I would consider it a
parameter in this case.

Or

V = E * kcat * S / (Km + S)

In this case the enzyme concentration is explicit and I would imagine in
this case that the E symbol could be treated as a modifier.

Herbert Sauro

-----Original Message-----
From: hrani@mailsvr.ncbs.res.in [mailto:hrani@mailsvr.ncbs.res.in]
Sent: Wednesday, December 15, 2004 10:23 PM
To: sbml-discuss@caltech.edu
Subject: [sbml-discuss] A model representation in SBML in which the
enzyme represented as a Modifier

Hi All,
I am developing a tool to convert genesis (.g) files to SBML format. Can
some one direct me to a model representation in SBML in which the enzyme
is displayed under Reaction structure expressed as a Modifier. Most of
the examples on the SBML repository don't show enzyme as Modifiers.

Regards
harsha

Ms.HarshaRani G.V.
Web:http://www.ncbs.res.in
Computational Neuroscience Lab, http://doqcs.ncbs.res.in
National Centre for Biological Sciences, Email:hrani@ncbs.res.in
Tata Institute of Fundamental Research, Phone:+91(80)23636420-28
UAS-GKVK Campus, Bangalore 560065 INDIA Extn.3231



      
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