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Forum: sbml-announce
 Topic: Introducing the 'sbml-announce' mailing list
Mike Hucka


Posts: 961
Registered:
October 2003
Introducing the 'sbml-announce' mailing list 26 Sep '06 23:43

In our continuing efforts to improve communications with the
SBML user community and revise the development process to
make it more transparent, accountable, timely and relevant,
we have introduced a new mailing list:

sbml-announce@caltech.edu

This is a broadcast-only mailing list for important
announcements concerning the Systems Biology Markup Language
(SBML). The release of new documents as well as errata and
revisions to old documents will be announced here.

We request that everyone who uses SBML in their software or
their work please sign up for the sbml-announce mailing
list, so that we may keep you informed about important
developments.

This is not a discussion list. It is strictly moderated by
humans to filter out any off-topic postings. Only the SBML
editors may post to the list. Only announcements of the
highest importance to SBML will be posted, including:

* Releases of specifications for new SBML Levels & Versions
* Disclosure of errata and subsequent issue of SBML revisions
* Requests for proposals for SBML technical development
* Voting topics and deadlines for SBML development issues
* Upcoming SBML community events (Forums and Hackathons)

The list membership will be kept confidential and will not
be intentionally disclosed beyond the SBML editors and their
immediate assistants. The list will not be used for
advertising.

In keeping with our normal policy, the list is opt-in
only; no one has been subscribed. You must subscribe
yourself using the following registration page:

https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

The goal is to move announcement-only type postings to
sbml-announce and *not* cross-post them to sbml-discuss.
(Example: announcements of meetings and new SBML
specification documents do not need to be cross-posted.) A
very few types of postings may end up being cross-posted if
it makes sense to do so. (Example: requests for proposals
of technical development may lead to discussions, so it
makes sense to have them show up on sbml-discuss.) In
summary, the goal is to keep cross-posting to a minimum.

Consequently, everyone should subscribe to sbml-announce
regardless of whether they are on sbml-discuss or
libsbml-discuss.

Thank you,
Mike

--
Mike Hucka, Ph.D. tel +1.626.395.8128
Senior Research Fellow, Control and Dynamical Systems
Co-director, Biological Network Modeling Center
The Beckman Institute @ The California Institute of Technology

      
 Topic: SBML Forum 2006: Oct. 12-13
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Forum 2006: Oct. 12-13 01 Oct '06 12:47

--------------------------------------------------------
11th Workshop on Software Platforms for Systems Biology:
The SBML Forum Meeting
--------------------------------------------------------

October 12 & 13, 2006
(immediately following ICSB 2006)

Location:
National Museum of Emerging Science & Innovation ("MeSci")
Tokyo, Japan

General information, agenda and registration page:
http://www.sbml.org/workshops/eleventh/

The next annual SBML Forum Meeting will be held in Tokyo,
Japan, as a satellite workshop of ICSB 2006. The venue will
be "MeSci"/Miraikan (http://www.miraikan.jst.go.jp), a
favorite location of past events in Japan. Please note
that, like some other ICSB workshops, the venue is actually
in Tokyo and not Yokohama (where ICSB itself will be held),
which means that you will probably want to change hotels.

A preliminary agenda is available on the meeting info page,
http://www.sbml.org/workshops/eleventh/. The first day will
be largely devoted to software talks from delegates, talks
about SBML experiences, a review of the final SBML Level 2
Version 2 specification, and related topics. The second day
will be largely devoted to SBML Level 3.

Prior to coming to the meeting, we strongly advise attendees
to print the detailed directions to the venue that we have
provided at http://www.sbml.org/workshops/eleventh/. (See
the section titled "Location" on that page.)

If you are planning on attending, please fill out the form
at http://www.surveymonkey.com/s.asp?u=694632374913 if you
have not already done so. We regret that we have no travel
support available for this meeting, and hope that attendees
can extend their ICSB 2006 stay in order to attend.

See you at the meeting!

The SBML Team

      
 Topic: Survey: SBML L2V2R2 versus L2V3 (deadline Feb.8)
Mike Hucka


Posts: 961
Registered:
October 2003
Survey: SBML L2V2R2 versus L2V3 (deadline Feb.8) 04 Feb '07 23:34

[This should have been posted to sbml-announce sooner.
Very sorry. It went to sbml-discuss but announcements of
votes are also supposed to go to sbml-announce. -- MH]

Dear SBML Community,

The discussion topic that produced the most significant
debate at the SBML Forum last October concerned the
inadequacy of the current L2V2 spec's use of the sboTerm
attribute. Specifically, the realization was that it needs
to be placed on several SBML elements where it is not
currently available. This can be done in one of two ways:
either the definitions of the individual objects where
sboTerm is missing can be redefined on a case-by-case basis,
or sboTerm can be moved to the SBase abstract class as an
optional attribute. In either case, the changes are
backward compatible in the sense that XML files containing
sboTerm attributes as currently defined in L2V2 would still
be exactly valid under either version of the fix. However,
and more seriously, either approach undeniably changes the
SBML object model.

This has put the SBML Editors in a bit of a quandary. The
guidelines under which we have been *trying* to work is that
changes to the syntax of SBML would only occur between
Versions within Levels (or else changing whole Levels). The
changes that are needed now come at the request of SBML
users, and are necessary to actually use SBO properly.
Further, some groups have begun using SBO, which is making a
fix an urgent matter. The changes *could* be done by making
them in a revision of L2V2 (i.e., in Level 2 Version 2
Revision 2), but that would violate (so soon!) the
guidelines we were trying to establish for good SBML
development. Under those guidelines, these kinds of syntax
changes *should* be done as a new Version (so, Level 2
Version 3). But if we create a Level 2 Version 3 so soon
after Level 2 Version 2 was released, will that leave a bad
impression and result in people losing confidence?

In defense of producing Level 2 Version 3, we note that (1)
it appears few people have worked on L2V2 support anyway,
apparently because most developers are waiting for a final
libSBML release with L2V2 support; (2) the SBML issue
tracker on http://sbml.org/issue-tracker now has numerous
small (albeit simple) changes on the table, including a
significant number of additional validation rules, which
suggests that producing a Level 2 Version 3 wouldn't be a
bad idea; (3) a Level 2 Version 3 specification could be
produced very quickly given the relatively simple changes on
the table; and (4) if it were done immediately, the
difference between L2V2 and a new L2V3 would be small enough
that even if someone was in the middle of implementing L2V2
support, they would probably not feel it is a difficult set
of changes to make to move to L2V3.

Either way, we believe we can produce a new document in
February, because of point #3 above.

So, here is our question for you. Assuming that either
alternative results in a release of an SBML specification
quickly, which of the following would you prefer is done?

1) Bend the guidelines and issue the changes as Revision 2
of Level 2 Version 2, or

2) Issue the changes as SBML Level 2 Version 3.

Please cast your votes by Feb. 8 using the following page:
http://www.surveymonkey.com/s.asp?u=872673185384

The SBML Level 2 Version 2 specification is at:
http://prdownloads.sourceforge.net/sbml/sbml-level-2-version-2-rev1.pdf?download

Thank you,
The SBML Editors
(Mike Hucka, Nicolas Le Novere, Sarah Keating,
Stefan Hoops, Andrew Finney)

      
 Topic: SBML Hackathon 2007: June 7-8
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Hackathon 2007: June 7-8 13 Apr '07 15:34

[I neglected to post this here last month; my apologies. --MH]

Announcing the

-------------------
SBML Hackathon 2007
-------------------
June 7-8, 2007
Newcastle University, UK
http://www.mas.ncl.ac.uk/~ncsg3/hackathon07/

Hosted by the
University of Newcastle upon Tyne, UK

We are pleased to announce that a site and dates have been
selected for the 2007 SBML Hackathon. The local organizers
this year are Colin Gillespie and Darren Wilkinson of the
School of Mathematics & Statistics at Newcastle University.

SBML Hackathons are an opportunity to get together with
other software developers who use SBML as their model
exchange format. The objective of the meeting is to
collaborate and exchange ideas and software to accelerate
development of SBML-enabled software. This year's Hackathon
main them will be the new SBML Level 2 Version 3 and working
with the (soon-to-be-released) final libSBML 3.0.

IMPORTANT: if you will be attending, please help us plan
local accommodations by filling out a very brief survey:

http://www.surveymonkey.com/s.asp?u=188773526823

We anticipate being able to cover the cost of local
accommodations, local ground transportation at Newcastle,
and some meals, for academic attendees. Transportation
to/from Newcastle and other remaining costs will be the
responsibility of attendees.

Newcastle, UK, is located in the northeastern region of
England, and has excellent links with the rest of the UK and
Europe by air, road, sea and rail. Please see the Hackathon
web page for more information about the location:

http://www.mas.ncl.ac.uk/~ncsg3/hackathon07/

You are encouraged to make flight reservations as soon as
possible because prices will likely increase in the coming
weeks.

Join us at the 2007 SBML Hackathon!

--
Mike Hucka and Colin Gillespie

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu.

[Updated on: 25 Sep '07 22:55] by Moderator

      
 Topic: SBML Level 2 Version 3 specification released
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 2 Version 3 specification released 16 Jun '07 16:16

Dear SBML-using community,

The SBML Editors are pleased to announce the release of the
SBML Level 2 Version 3 specification, now available from
http://sbml.org/documents/ as well as the SBML project
on SourceForge.net.

This new version of the SBML Level 2 specification
incorporates many corrections and clarifications. The
following is a short summary of some of the major changes;
a more detailed list is provided in Appendix G of the
document.

- Placement of the 'sboTerm' attribute on SBase instead of
only some individual object classes, and expansion of the
SBO hierarchy and the mapping of SBML objects to SBO

- Removal of 'timeUnits' from Event

- Removal of 'spatialSizeUnits' from Species

- Explanations of some differences in data type definitions
between XML Schema and MathML

- Explanation of the units assumed for literal numbers
appearing in mathematical expressions, along with
corrections to validation rules.

- Explanations of the units required by various MathML
operators and other constructs

- Corrections to the definitions of some primitive data types

- Addition of more guidelines about the content of
<annotation> elements.

- Addition of more validation rules

- Complete redrawing of all class definition diagrams to use
more proper UML

Please report issues with the SBML L2v3 specification using
the reporting facilities at

http://sbml.org/issue-tracker

We would like to thank all of the many members of the SBML
community for their current support and use of SBML.


Mike Hucka
Nicolas Le Novere
Sarah Keating
Stefan Hoops
Andrew Finney


____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu.

[Note added by moderator 2007-Jun-25: the original message had an incorrect subject line. This archived message has been edited to make the correction, thereby hopefully reducing confusion and making search easier for users of this web forum. The original message is still untouched in the sbml-announce@caltech.edu mailing list archive. -- Mike Hucka]

[Updated on: 25 Jun '07 11:42] by Moderator

      
 Topic: SBML Forum 2007: Oct. 5-6
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Forum 2007: Oct. 5-6 22 Aug '07 23:01

--------------------------------------------------------
12th Workshop on Software Platforms for Systems Biology:
The SBML Forum Meeting
--------------------------------------------------------

October 5 & 6, 2007
(immediately following ICSB 2007, http://icsb-2007.org)

Location:
Long Beach Convention Center
Long Beach, California

Workshop registration page:
http://surveymonkey.com/s.aspx?sm=XEp1nZuPNCdEPpPfJpMqDQ_3d_3d

General information page:
http://www.sbml.org/workshops/twelfth/

The next annual SBML Forum Meeting will be held in Long
Beach, California, USA, as a satellite workshop of ICSB
2007. Although the exact agenda has not been set and
depends in part on the wishes of the attendees, this next
Forum meeting will likely focus on moving forward with SBML
Level 3 development. A more detailed agenda for the meeting
will be forthcoming.

If you are planning on attending, please fill out the form
at the URL given above as soon as possible. We regret that
we have no travel support available for this meeting, and
hope that potential attendees can extend their ICSB 2007
stay in order to attend.

As in past SBML Forum meetings, there will be a block of
time available during the meeting for people to give short
presentations (5-10 minutes) to the audience on the
following topics: SBML-enabled applications, the use of SBML
to integrate different applications, proposals for SBML
extensions, proposals for standards that compliment SBML,
announcements of software or standards or events of interest
to SBML users, and general experiences of using SBML "in the
field". The registration page provides the opportunity for
you to indicate if you would like to make a presentation.

We hope to hear from you soon.

The SBML Team

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu.

      
 Topic: Release 2 of SBML Level 2 Version 3 is now available
Mike Hucka


Posts: 961
Registered:
October 2003
Release 2 of SBML Level 2 Version 3 is now available 28 Sep '07 09:51

Dear SBML community,

The SBML Editors are pleased to release a minor update to
the SBML Level 2 Version 3 specification, in the form of
Release 2. This release makes no SBML language changes that
were not intended to be in Release 1; rather, it makes
corrections for issues and errors that have come to light
since the announcement of Release 1. These issues are
documented in detail in the new Appendix H of the document
and can also be found online at the following URL:

http://sbml.org/specifications/sbml-level-2/version-3/errata/

There are some particularly unfortunate typographical errors
in the examples and explanations of SBML reactions in the
first release of Level 2 Version 3, so if you have been
scratching your head over some of the equations in Release
1, the Release 2 update may resolve the questions for you.

A PDF version of the SBML Level 2 Version 3 specification is
available for immediate download from SourceForge at

http://sourceforge.net/project/showfiles.php?group_id=71971

The file is called "sbml-level-2-version-3-rel-2.pdf". You
can also find a direct link at

http://sbml.org/specifications/sbml-level-2/version-3

Please report any issues you find in the new release using
the online tracker at http://sbml.org/issue-tracker

The SBML Editors.

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu.

      
 Topic: SBML Hackathon 2008: April (6)-7-8
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Hackathon 2008: April (6)-7-8 19 Feb '08 10:38

Announcing the
-------------------
SBML Hackathon 2008
-------------------

April (6)-7-8
Stellenbosch University
Stellenbosch, South Africa
http://www.jjj.sun.ac.za/hackathon/

Hosted by the
JJJ Group, Stellenbosch University

SBML Hackathons are an opportunity to get together with
other software developers who use SBML as their model
exchange format. The objective of the meeting is to
collaborate and exchange ideas and software to accelerate
development of SBML-enabled software.

This year's Hackathon will also include discussions of the
upcoming SBML Test Suite and plans for modularizing libSBML
to support SBML Level 3.

The SBML Hackathon will be at Stellenbosch University. The
local organizers this year are Jannie Hofmeyr, Johann Rohwer
and Brett Olivier. The city of Stellenbosch is located
approximately 30 kilometers from Cape Town, South Africa. A
few pictures and some brief information can be found here:
http://www.stellenboschwriters.com/stboschm.html

SBML Hackathons have traditionally been two-day events, but
with the growth of the global SBML effort, the growing size
of the SBML community, and the distances some people have to
travel to reach the event, we are experimenting this year
with 2.5 days by adding an optional half day beginning on
the afternoon of April 6. (Having the extra day in front
also accounts for the fact that many flights to South Africa
are overnight flights arriving in the morning on April 6.)

We anticipate being able to cover the cost of local
accommodations, local ground transportation at Stellenbosch,
and some meals, for academic attendees. Transportation
to/from Stellenbosch and other remaining costs will be
partly the responsibility of attendees, although the Caltech
group anticipates being able to provide a portion of the
funding for those who cannot attend otherwise.

If you will be attending the Hackathon, please fill out the
following 2 short surveys:

About your attendance: http://tinyurl.com/yrtcoe
About your flight schedule: http://tinyurl.com/294nnu

Best regards,
Mike (on behalf of everyone)

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu.

      
 Topic: SBML Forum 2008: Aug. 27-28
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Forum 2008: Aug. 27-28 02 May '08 12:07

--------------------------------------------------------
13th Workshop on Software Platforms for Systems Biology:
The SBML Forum Meeting
--------------------------------------------------------

August 27 & 28, 2008
(as a workshop at ICSB 2008, http://icsb-2008.org)

Location:
Gothenburg Convention Centre
Gothenburg, Sweden

Workshop registration page:
http://sbml.org/Events/Workshops/The_13th_SBML_Forum_Meeting/Survey

General information page:
http://sbml.org/Events/Workshops/The_13th_SBML_Forum_Meeting

The next annual SBML Forum Meeting will be held in
Gothenburg, Sweden, as a satellite workshop of ICSB 2008.
The exact agenda has not been set and depends in part on the
wishes of the attendees; a more detailed agenda for the
meeting is forthcoming.

If you are planning on attending, please fill out the form
at the URL given above as soon as possible. We regret that
we have no travel support available for this meeting, and
hope that potential attendees can extend their ICSB 2008
stay in order to attend. We will, however, arrange for
coffee breaks and (hopefully) some meals.

As in past SBML Forum meetings, there will be a block of
time available during the meeting for people to give short
presentations (5-10 minutes) to the audience on the
following topics: SBML-enabled applications, the use of SBML
to integrate different applications, proposals for SBML
extensions, proposals for standards that compliment SBML,
announcements of software or standards or events of interest
to SBML users, and general experiences of using SBML "in the
field". The registration page provides the opportunity for
you to indicate if you would like to make a presentation.

We hope to hear from you soon.

The SBML Team

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/Forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu

      
 Topic: SBML Hackathon 2009: March 26-28
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Hackathon 2009: March 26-28 10 Dec '08 14:20

Announcing the
-------------------
SBML Hackathon 2009
-------------------

http://sbml.org/Events/Hackathons/The_7th_SBML_Hackathon

March 26-28
European Bioinformatics Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge CB10 1SD
United Kingdom

Hosted and co-organized by the
Le Novere group (http://ebi.ac.uk/compneur)

SBML Hackathons are an opportunity to get together with other
software developers who use SBML as their model exchange
format. The objective of the meeting is to collaborate and
exchange ideas and software to accelerate development of
SBML-enabled software.

The 2009 SBML Hackathon will be held at the familiar EBI in
Hinxton, UK, which was also the site of the 2004 SBML
Hackathon. The EBI is the home of many SBML-related efforts
and resources, including the BioModels Database, the Systems
Biology Ontology, MIRIAM Resources, and more.

This year's event will be immediately followed by the
BioModels Annual Meeting, held March 28-30. Interested
persons may register for one or both events using the
registration page at

http://moourl.com/sb2009

This year's Hackathon is also preceded by BioSysBio on March
23-25 in Cambridge (http://conferences.theiet.org/biosysbio/)
and will be followed shortly thereafter by the combined
CellML-SBGN-SBO-MIRIAM-BioPAX super-workshop in Auckland, New
Zealand, April 5 (http://www.cellml.org/workshop/workshop2009/)

Please visit the SBML Hackathon 2009 information page for more
information, and please make sure to fill out the registration
form as soon as you can:

http://sbml.org/Events/Hackathons/The_7th_SBML_Hackathon

We will have a limited amount of travel support funding
available for the SBML/BioModels events. We emphasize
*limited amount*. If you truly need it, please get in touch
with us as soon as possible and we will try to work something
out.

We hope to see you all there in 2009!

Mike, the Le Novere group, and the SBML Team

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/Forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu

      
 Topic: SBML Level 2 Version 4 specification released
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 2 Version 4 specification released 22 Dec '08 21:59

Dear SBML-using community,

The SBML Editors are pleased to announce the release of the
SBML Level 2 Version 4 specification, now available from
http://sbml.org/Documents/Specifications as well as the SBML
project on SourceForge.net.

This new version incorporates changes requested by the SBML
community via past votes and SBML Forum meetings, as well as
numerous smaller corrections for inconsistencies. The
following is a short summary of the major changes; more
explanations of the changes are provided in Appendix G of
the document, and the textual changes (relative to L2 V3
Release 2) are marked in red throughout the document. The
details of all major issues are also logged as tracker items
in the SBML issue tracker (http://sbml.org/issue-tracker)
under the category "Level 2 Version 3".

- Unit consistency is not *required* for a valid SBML model,
following the decision made via a vote taken in late 2007.

- Removal of prohibition on forward references in
user-defined function definitions.

- Removal of prohibition on forward references in the
Compartment 'outside' attribute.

- Corrections to small syntax error in the RDF defined for
annotations.

- New flag "useValuesFromTriggerTime" on Event allows a
model to indicate when EventAssignment formulas are meant
to be evaluated.

- Clarification about the relationship of compartment sizes
when one compartment is outside of another.

- Addition of new MIRIAM qualifiers.

- Updates for SBO and values allowed for sboTerm.

- Removal of irrelevant or no longer applicable validation
rules, and addition of new rules for the changes above.

- "Built-in SBML units" are now called "predefined SBML
units", to be (hopefully) more clear.

- Other minor corrections and edits.

Please report issues with the SBML Level 2 Version 4
specification using the issue-tracker.

We would like to thank all of the many members of the SBML
community for their current support and use of SBML.

Mike Hucka
Nicolas Le Novere
Sarah Keating
Stefan Hoops
Sven Sahle
Darren Wilkinson

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/Forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu

      
 Topic: New errata for SBML Level 2 Version 4
Mike Hucka


Posts: 961
Registered:
October 2003
New errata for SBML Level 2 Version 4 11 May '09 21:45

I'd to draw people's attention to the recent official
issuance of some minor errata statements for the SBML Level
2 Version 4 Release 1 specification. You can find the list at

http://sbml.org/Documents/Specifications

(click on the blue icon next to "Errata" in the Level 2
Version 4 section). At some point in the future, there will
be a Release 2 of the specification to fix the errata.

As always, we greatly welcome reports of any issues found in
the SBML specifications. You can find a link to the issue
tracking/reporting system in the same section on the page
mentioned above.

Thank you.

Mike, on behalf of the SBML Editors

____________________________________________________________
To manage your sbml-announce list subscription, visit
https://utils.its.caltech.edu/mailman/listinfo/sbml-announce

For a web interface to the sbml-announce mailing list, visit
http://sbml.org/Forums/

For questions or feedback about the sbml-announce list,
contact sbml-team@caltech.edu

      
 Topic: SBML Forum 2009: September 3-4
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Forum 2009: September 3-4 17 May '09 15:44

--------------------------------------------------------
14th Workshop on Software Platforms for Systems Biology:
The SBML Forum Meeting
--------------------------------------------------------

September 3 & 4, 2009
(as a workshop at ICSB 2009, http://icsb-2009.org)

Location:
Stanford University
California, USA

General information page:
http://sbml.org/Events/Workshops/The_14th_SBML_Forum_Meeting

The next annual SBML Forum Meeting will be held in
California, USA, as a satellite workshop of ICSB 2009. The
exact agenda has not yet been set and depends in part on the
wishes of the attendees; a more detailed agenda for the
meeting is forthcoming.

If you are planning on attending, please fill out the survey
form at the URL given above as soon as possible. As in past
SBML Forum meetings, there will be a block of time available
during the meeting for people to give short presentations
(5-10 minutes) to the audience on the following topics:
SBML-enabled applications, the use of SBML to integrate
different applications, proposals for SBML extensions,
proposals for standards that compliment SBML, announcements
of software or standards or events of interest to SBML
users, and general experiences of using SBML "in the field".
The survey page provides the opportunity for you to indicate
if you would like to make a presentation.

We regret that we have no travel support available for this
meeting, and hope that potential attendees can extend their
ICSB 2009 stay (for those who are going to ICSB) in order to
attend.

You are not required to attend ICSB 2009 in order to attend
the SBML Forum. However, ICSB 2009 requires that all
workshop attendees register and pay a small fee (US $45) to
defray costs of facilities and other expenses. To do that,
please visit

http://icsb-2009.org

and follow the registration link.

We hope to hear from you soon.

The SBML Team

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 Topic: Additional errata for SBML Level 2 Version 4
Mike Hucka


Posts: 961
Registered:
October 2003
Additional errata for SBML Level 2 Version 4 11 Jul '09 09:11

I'd to draw people's attention to some recent additions to
the official list of minor errata in the SBML Level 2
Version 4 Release 1 specification. You can find the list at

http://sbml.org/Documents/Specifications

(click on the blue icon next to "Errata" in the Level 2
Version 4 section). At some point in the future, there will
be a Release 2 of the specification to fix the errata.

As always, we greatly welcome reports of any issues found in
the SBML specifications. You can find a link to the issue
tracking/reporting system in the same section on the page
mentioned above.

Thank you.

Mike, on behalf of the SBML Editors

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 Topic: SBML Level 3 Version 1 Core, Release 1 Candidate
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 3 Version 1 Core, Release 1 Candidate 31 Dec '09 20:55

Dear SBML-using community,

The SBML Editors are pleased to announce the availability
of the Release 1 Candidate specification for
SBML Level 3 Version 1 Core. It is now available from

http://sbml.org/Documents/Specifications

and the SBML project on SourceForge.net. It will shortly be
available from Nature Precedings as well.

This specification is labeled "Release 1 Candidate" until
two independent software implementations are reported by the
SBML-using community. At that time, if no significant
errors are reported, the specification will be considered
final. Release 1 of SBML Level 3 Version 1 Core will not be
modified further unless errors are found.

Please report issues with this specification using the
simple, streamlined reporting form indicated on the front
page of the specification and on the sbml.org pages. (It's
a live link -- just click it to be sent to the web form.)

An explanation is warranted regarding one issue: unlike past
specification documents, there are no XML Schemas in this
one. Our plan is to create and issue the schemas as
separate companion documents, and to produce RELAX NG
schemas and probably also Schematron schemas, instead of XML
Schemas. Thus, there will be forthcoming documents titled
"The Systems Biology Markup Language (SBML): RELAX NG Schema
for Level 3 Version 1 Core", etc.

We would like to thank all of the many members of the SBML
community for their current support and use of SBML. (And a
special thanks to Nicolas Le Novere for extra feedback this
past week.)

The 2009 SBML Editors:
Mike Hucka
Frank Bergmann
Sarah M. Keating
Stefan Hoops
Sven Sahle
Darren J. Wilkinson

____________________________________________________________
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 Topic: The 2010 SBML-BioModels.net Hackathon
Mike Hucka


Posts: 961
Registered:
October 2003
The 2010 SBML-BioModels.net Hackathon 22 Jan '10 15:47

Announcing the
-------------------------------------
2010 SBML & BioModels.net Hackathon
-------------------------------------

May 1-4, 2010
University of Washington
Seattle, WA, USA

Hosted and co-organized by the
Sauro Group (http://sys-bio.org)

*** Planning on attending? PLEASE TELL US using this form: ***

http://tinyurl.com/hackathon2010

Hackathons are an opportunity to get together with other
software developers. This year's event follows last year's
approach of combining the traditional SBML Hackathon with
the BioModels.net meeting, and this year it will be even
more integrated. The "SBML-BioModels.net Hackathon" is an
opportunity to gather developers and researchers who use
SBML and BioModels.net (BioModels Database, SBO, MIRIAM,
SED-ML) resources, to collaborate and exchange ideas and
software and thereby accelerate development of both SBML and
BioModels.net resources.

This year's event is being hosted by the Sauro Group in the
University of Washington Department of Bioengineering. A
preliminary agenda is now available online at

http://sbml.org/Events/Hackathons/The_2010_SBML-BioModels.net_Hackathon

Please tell us if you are planning on attending by filling
out the very short attendance survey. This will help us
plan an appropriate number of hotel rooms and other things.
The survey link is on the event page; here's a shortcut:

http://tinyurl.com/hackathon2010

We hope to see you all there in 2010!

Mike
on behalf of the local organizers and the SBML Team

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[Updated on: 22 Jan '10 15:48] by Moderator

      
 Topic: 3 more errata in SBML Level 2 Version 4
Mike Hucka


Posts: 961
Registered:
October 2003
3 more errata in SBML Level 2 Version 4 10 Feb '10 00:24

I'd to draw people's attention to some recent additions to
the official list of errata in the SBML Level 2 Version 4
Release 1 specification. You can find the list at

http://sbml.org/Documents/Specifications

(click on the blue icon next to "Errata" in the Level 2
Version 4 section). At some point in the future, there will
be a Release 2 of the specification to fix the errata.

As always, we greatly welcome reports of any issues found in
the SBML specifications. You can find a link to the issue
tracking/reporting system in the same section on the page
mentioned above.

Thank you.

Mike, on behalf of the SBML Editors

____________________________________________________________
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 Topic: REMINDER: Registration to COMBINE2010
Nicolas Le Novere


Posts: 469
Registered:
October 2003
REMINDER: Registration to COMBINE2010 07 Aug '10 01:53

Announcing the:

###############################################
# #
# First COMBINE meeting #
# #
###############################################

Dear Colleague,

We are pleased to announce COMBINE 2010, that will take place at the
Informatics Forum in Edinburgh, Scotland, on Oct. 6–9, 2010.

With COMBINE 2010, we are inaugurating a new, broader series of meetings to
replace, among other events, the SBML and SBGN Fora or the BioPAX face to
face meetings. The new meetings are a recognition of the fact that there
are multiple allied standardization efforts that should work together
towards smooth interoperability. Moreover, we believe a joined meeting
makes good economic sense: compared to multiple separate workshops, they
reduce the overall number of meetings, travel, and money spent. To reflect
this broad scope, we are calling the new workshop series ''COMBINE'':

COMBINE: the COmputational Modeling in BIology NEtwork

This first meeting will feature sessions about the following efforts:
BioPAX, CellML, SBGN, SBML and SED-ML. In addition, sessions will be
dedicated to interconversion (how to generate one format from another) and
interoperability (i.e. how to make the formats work together). A more
detailed agenda will be announced later. The activities at COMBINE will be
similar to typical workshops, with oral and poster presentations, break-out
discussions, and more.

You can find a webpage describing the meeting at

http://sbml.org/Events/Forums/COMBINE_2010

(sbml.org being a temporary location before setting up an independent
website for the COMBINE and HARMONY meetings.).

In order to be able to tune the agenda of COMBINE and satisfy the largest
number of attendees, we need you to register *as soon as possible* at:

http://www.surveymonkey.com/s/9GP9KJ3

The organizers:

* Nadia Anwar, Sloan Kettering Institute
* Emek Demir, Sloan Kettering Institute
* Michael Hucka, California Institute of Technology (Caltech)
* Camille Laibe, European Bioinformatics Institute (EMBL-EBI)
* Nicolas Le Novère, European Bioinformatics Institute (EMBL-EBI)
* Catherine Lloyd, Auckland Bioengineering Institute
* Stuart Moodie, University of Edinburgh
* Anatoly Sorokin, University of Edinburgh
____________________________________________________________
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[Updated on: 25 Aug '10 08:13] by Moderator

      
 Topic: SBML 10th Anniversary Symposium
Mike Hucka


Posts: 961
Registered:
October 2003
SBML 10th Anniversary Symposium 04 Oct '10 06:02

------------------------------------------------------
The SBML 10th Anniversary Symposium
http://sbml.org/Events/SBML_10th_Anniversary_Symposium
------------------------------------------------------

The first draft definition of the Systems Biology Markup Language (SBML) was produced over the summer 2000. Since that time, it has become a de facto standard in computational systems biology, supported by over 180 software tools, and a catalyst for numerous related standardization efforts.

To celebrate ten years of SBML, we are holding a special symposium on the afternoon of October 9th, 2010, in Edinburgh, UK, immediately before ICSB 2010 and after COMBINE 2010. Speakers include:

* Hiroaki Kitano
* John C. Doyle
* Hamid Bolouri
* Herbert M. Sauro
* Pedro Mendes
* Andrew M. Finney
* Michael Hucka
* Nicolas Le Novère

The event will run 13:30 to 18:00, followed by cake and refreshments. The location will be the Informatics Forum:

Informatics Forum
10 Crichton Street
Edinburgh EH8 9AB

The event is open to all. Please join us!

Nicolas Le Novère & Mike Hucka
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 Topic: SBML Level 3 Version 1 Core, Release 1 (final)
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 3 Version 1 Core, Release 1 (final) 05 Oct '10 22:43

The SBML Editors are pleased to announce the release of the
final specification for SBML Level 3 Version 1 Core. It is
available now from

http://sbml.org/Documents/Specifications

and the SBML project on SourceForge.net. It will soon be
available from Nature Precedings as well.

This release of the specification incorporates the results
of the community vote held earlier this year regarding
changes to the definition of events. That is the most
significant change from the candidate release of L3V1 Core.
In addition, this release includes are a number of small
corrections for errors found in the candidate specification.

Note this is not a candidate release: it is a final release.
The condition for calling this specification "final" is the
availability of at least two software systems that
demonstrate (to a reasonable degree) the implementation of
the specification. During the development of this
specification, two implementations (iBioSim and RoadRunner)
tested the new features. In fact, the previous release 1
candidate had at least 3 known implementations (BioUML,
iBioSim, RoadRunner). In consideration of all this, the
SBML Editors believe it is time to call this release final.

We would like to thank all of the many members of the SBML
community for their current support and use of SBML. The
following people deserve special mention in regards to this
specification's release:

* Chris Myers for extensive discussions, software
implementation and testing of events features and
definitions

* Sarah Keating for implementing test cases and libSBML
support

* Allyson Lister, for logging a staggering 40+ bug reports
for the previous candidate spec

* Nick Juty and Camille Laibe for updates to the SBO
annotations sections

The SBML Editors
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 Topic: HARMONY 2011: April 18-22 in New York City
Mike Hucka


Posts: 961
Registered:
October 2003
HARMONY 2011: April 18-22 in New York City 19 Jan '11 21:00

Announcing H A R M O N Y 2011

Dates: April 18-22, 2011
Place: New York City, USA
Website: http://www.biopax.org/harmony.php
Hosts: CBIO @ Memorial Sloan-Kettering Cancer Center

Attendance survey: http://www.surveymonkey.com/s/V2B7FZN

As most of you hopefully know, beginning this year, we are moving to making SBML Hackathons be part of a wider-scoped event named HARMONY: the HAckathon on Resources for MOdeliNg in biologY.

HARMONY 2011 will take place from April 18-22, at the Memorial Sloan-Kettering Cancer Center, New York City, USA. HARMONY events are joint meetings between the developers of formats and related standards supporting computational modeling in biology, including but not limited to SBML, SBGN, BioPAX, and others. Unlike the annual COMBINE meetings, HARMONY is not a general forum targeting the community of users at large, but rather a technical meeting aimed at bringing together developers of the standards and software implementing them.

Please help us make the best possible arrangements for this meeting by registering as soon as you can using the short form at http://www.surveymonkey.com/s/V2B7FZN

We hope to see you there!

Best regards,
Nadia Anwar and Mike Hucka, on behalf of all the organizers

[Updated on: 20 Jun '12 12:43] by Moderator

      
 Topic: COMBINE 2011: September 3-7 in Heidelberg
Mike Hucka


Posts: 961
Registered:
October 2003
COMBINE 2011: September 3-7 in Heidelberg 14 Jun '11 15:30

COMBINE 2011, the second international meeting of the COmputational Modeling in BIology NEtwork will take place September 3-7, in Heidelberg, Germany. COMBINE integrates and replaces previous individual meetings of several standardization efforts, including the annual SBML Forum.

Registration for COMBINE 2011 is now open. Early bird registration ends July 15, so please register at your earliest convenience. Visit the following web page for the registration link and more information about COMBINE 2011:

http://co.mbine.org/events/COMBINE_2011

Attendees are responsible for arranging their own accommodations. We urge you to make your hotel bookings as soon as possible, because Heidelberg in September is a popular tourist destination and hotels fill early.

The organizations of COMBINE 2011 are (in alphabetical order):
* Gary Bader, University of Toronto, Canada

* Emek Demir, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, USA

* Martin Golebiewski, Heidelberg Institute for Theoretical Studies (HITS), Germany

* Michael Hucka, California Institute of Technology (Caltech), USA

* Nicolas Le Novère, European Bioinformatics Institute (EMBL-EBI), UK

* Sven Sahle, BioQuant at the University of Heidelberg, Germany

COMBINE 2011 will be hosted by the Heidelberg Institute for Theoretical Studies (HITS).

Thank you, and we hope to see you at COMBINE 2011!
____________________________________________________________
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[Updated on: 14 Jun '11 15:34] by Moderator

      
 Topic: HARMONY 2012: May 21-25 in Maastricht
Mike Hucka


Posts: 961
Registered:
October 2003
HARMONY 2012: May 21-25 in Maastricht 07 Mar '12 20:18

***********************************************

Announcing

H A R M O N Y 2012

May 21-25, 2012
Maastricht, The Netherlands

http://co.mbine.org/events/HARMONY_2012

***********************************************


Dear Colleagues,

We are happy to announce that the registration for HARMONY 2012 is open now.

HARMONY is a hackathon-type meeting, with a focus on development of the standards, interoperability and infrastructure. There is generally not many general discussions or oral presentations during HARMONY; instead, the time is devoted to allowing hands-on hacking and interaction between people focused on practical development of software and standards. The HARMONY 2012 meeting will be hosted by the Department of Bioinformatics from Maastricht University.

The maximum number of participants is 70. Please register using the following form:

http://harmony2012.eventbrite.com

We are trying to get more funding to support the accommodation costs of the participants. We have agreed to special room rates with the Apart Hotel Randwyck and the NH hotel. The participants have to book the hotel rooms themselves. For further information please have a look at

http://www.co.mbine.org/events/HARMONY_2012#Accommodation

The conference dinner will take place on the evening of Wednesday 23rd May at Ipanema. On the first meeting day (Monday 21st May) there will be an open symposium with tutorials, talks and a reception/poster session in the evening.

A full schedule and further information will be provided on the meeting website

http://www.co.mbine.org/events/HARMONY_2012

We look forward to welcoming you all in Maastricht. For any further questions, please contact us (harmony2012@maastrichtuniversity.nl).

Best Regards,
Martina, Chris, Gary, Nicolas, Mike
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[Updated on: 08 Mar '12 11:28] by Moderator

      
 Topic: COMBINE 2012: August 15-19 in Toronto
Mike Hucka


Posts: 961
Registered:
October 2003
COMBINE 2012: August 15-19 in Toronto 29 Jun '12 11:52

The Computational Modeling in Biology Network (COMBINE) is an initiative to
coordinate the development of the various community standards and formats,
initially in Systems Biology and related fields. The Annual COMBINE forum
is a workshop-style event with oral presentations, posters and breakout
sessions. The meeting provides an opportunity for those involved in many
related standardization and software efforts in systems biology to meet and
discuss their efforts, with the aim of working more closely together to
ensure smooth interoperability between systems.

http://co.mbine.org/events/COMBINE_2012

COMBINE 2012 will take place at The Donnelly Centre building at the
University of Toronto from Wednesday August 15 to Sunday Aug. 19, 2012,
immediately preceding the 13th International Conference on Systems Biology
(http://icsb2012toronto.com/). The COMBINE conference location is a short
walk from ICSB events and COMBINE 2012 is an official satellite meeting of
ICSB, so you can follow the same travel and accommodation instructions for
ICSB and use the same hotel discounts. Registration for COMBINE is $125
(Canadian) to cover costs associated with the meeting, including a workshop
dinner and catering.

We hope to see you there!
____________________________________________________________
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 Topic: Errata for SBML Level 3 Version 1 Core specification
Mike Hucka


Posts: 961
Registered:
October 2003
Errata for SBML Level 3 Version 1 Core specification 03 Jul '12 17:50

The SBML Editors have collected and published a list of officially-recognized issues in the SBML Level 3 Version 1 Core Release 1 specification document. You can view the list by visiting

http://sbml.org/Documents/Specifications#SBML_Level_3

and clicking on the icon labeled "Errata".

As always, we greatly welcome reports of any issues found in the SBML specifications. You can find a link to the issue tracking/reporting system in the same section on the page mentioned above.

Thank you.

Mike, on behalf of the SBML Editors
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 Topic: ICSB/COMBINE Tutorial: Modelling and Simulation of Quantitative Biological Models
martin.golebiewski


Posts: 5
Registered:
March 2011
ICSB/COMBINE Tutorial: Modelling and Simulation of Quantitative Biological Models 31 Jul '12 08:39

A joint tutorial at the International Conference on Systems Biology (ICSB) and the COMBINE 2012 meeting will be of special interest for the SBML community:

**** Modelling and Simulation of Quantitative Biological Models: COPASI, CellDesigner, JWS online, SABIO-RK and Virtual Cell ****

In this tutorial participants will learn setting-up quantitative computer models of biological networks using experimental kinetic data and simulating them in different systems biology platforms. Hands-on sessions, lectures and software demonstrations will be included providing attendees with the necessary skills to enable them to access experimental kinetics data from available resources, assembling computer models with these data and finally simulating the models within different tools.

** Date and Venue **
Sunday, August 19, 2012, 9:00 am - 2:30 pm
Donnelly Centre for Cellular and Biomolecular Research (CCBR)
University of Toronto, 160 College Street
Toronto M5S 3E1, Canada


** Target audience **
Modellers and experimentalists with some basic experience in modelling and simulation of biological networks


The participation is free of charge. Details are in the attached outline.

Please register at
https://www.surveymonkey.com/s/icsb2012_workshops


Best regards,
Martin Golebiewski
(on behalf of the organizers)

Attachment: ICSBTutorial2012.pdf
(Size: 59.84KB, Downloaded 296 time(s))
      
 Topic: SBML Level 3 Flux Balance Constraints package
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 3 Flux Balance Constraints package 14 Feb '13 08:41

The working group for the SBML Level 3 "Flux Balance Constraints" package is pleased to announce that Version 1 of the specification is now available. You can find a link to the specification, as well as other information, from the 'fbc' package status page at

http://sbml.org/Documents/Specifications/SBML_Level_3/Packages/fbc

Special thanks to Brett Olivier and Frank Bergmann for authoring the specification and pushing the package along through the SBML Development Process.

This marks an exciting milestone in the effort to standardize model descriptions and enhance tool interoperability in the constraint-based modeling area.

Best regards,
Mike (on behalf of Brett and Frank, and the rest of the FBC working group)
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[Updated on: 14 Feb '13 09:08] by Moderator

      
 Topic: SBML Level 3 Hierarchical Model Composition package
Mike Hucka


Posts: 961
Registered:
October 2003
SBML Level 3 Hierarchical Model Composition package 14 Feb '13 08:52

[This is a belated announcement; this should have been posted on sbml-announce back in November -- MH]

The working group for the SBML Level 3 "Hierarchical Model Composition" package is pleased to announce that Version 1 of the specification is now available. You can find a link to the specification, as well as other information, from the 'comp' package status page at

http://sbml.org/Documents/Specifications/SBML_Level_3/Packages/Hierarchical_Model_Composition_%28comp%29

Special thanks to Lucian Smith, Stefan Hoops, Chris Myers, Nicolas Le Novère, Frank Bergmann, Andrew Finney, Martin Ginkel, Jörg Stelling, Ranjit Randhawa, Michael Blinov, Wolfram Liebermeister, and Ion Moraru for their contributions to the development of the 'comp' package over the years, and especially Lucian Smith for pushing the package along through the SBML Development Process and authoring the bulk of the final specification document.

Best regards,
Mike (on behalf of the 'comp' package working group)
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 Topic: HARMONY 2013: May 20-23 in Farmington, CT, USA
Mike Hucka


Posts: 961
Registered:
October 2003
HARMONY 2013: May 20-23 in Farmington, CT, USA 20 Feb '13 11:26

HARMONY 2013 is kindly being organized by the Virtual Cell group at the
University of Connecticut Health Center, USA. It will take place from May
20 to 23. Registration is now open!

http://www.co.mbine.org/events/HARMONY_2013
____________________________________________________________
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 Topic: ICSB Tutorial: Modelling and Simulation of Quantitative Biological Models on September 4th, 2013
martin.golebiewski


Posts: 5
Registered:
March 2011
ICSB Tutorial: Modelling and Simulation of Quantitative Biological Models on September 4th, 2013 29 Apr '13 06:18

Dear colleagues,

We cordially invite you to this full-day COMBINE (http://co.mbine.org/) tutorial workshop:

Modelling and Simulation of Quantitative Biological Models
Wednesday, September 4th, 2013 (9:30 - 17:30)
Copenhagen (at the Technical University of Denmark)

This workshop is a satellite of the 14th International Conference on Systems Biology (ICSB). You can sign in for the tutorial (free of charge) when registering for the conference at http://www.icsb2013.dk.


Participants will learn setting-up quantitative computer models of biological networks using experimental kinetic data and simulating them in different systems biology platforms. Hands-on sessions, lectures and software demonstrations will be included providing attendees with the necessary skills to enable them to access experimental kinetics data from available resources, assembling computer models with these data and finally simulating the models within different tools.

The topics will include:
* Using experimental data for setting up quantitative models
* Parameter estimation, optimization and model fitting
* Simulation, analysis and visualization of biochemical models
* Integrated data management and model databases
* Community standards and formats for systems biology models


Covered tools, platforms, databases and standards:

BioModels database: http://www.ebi.ac.uk/biomodels-main/
CellDesigner: http://www.celldesigner.org/
COMBINE: http://co.mbine.org/
COPASI: http://www.copasi.org
JWS Online/OneStop: http://jjj.biochem.sun.ac.za/
SABIO-RK: http://sabio.h-its.org/
SBML: http://sbml.org
SYCAMORE: http://sycamore.eml.org
SysMO-DB: http://www.sysmo-db.org/
Virtual Cell (VCell): http://www.nrcam.uchc.edu/
Virtual Liver SEEK: http://seek.virtual-liver.de/


Target audience:
Modellers and experimentalists with some basic experience in modelling and simulation of biological networks.


Tutors:
Martin Golebiewski, Frank Bergmann, Akira Funahashi, Noriko Hiroi, Mike Hucka, Nicolas Le Novère, Pedro Mendes, Ion Moraru, Sven Sahle, Jacky Snoep, Dawie van Niekerk, Andreas Weidemann, Katy Wolstencroft


Best regards,

Martin Golebiewski


Phone: +49-6221-533-281
FAX: +49-6221-533-298
Email: martin.golebiewski@h-its.org

HITS gGmbH
Schloss-Wolfsbrunnenweg 35
D-69118 Heidelberg
Germany

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Forum: jsbml-development
 Topic: On-line SBML Validator
Sarah Keating


Posts: 413
Registered:
May 2004
On-line SBML Validator 28 Oct '09 06:41

Hi Guys

FYI there is information here on using the SBML online validator as a
web service:

http://sbml.org/Facilities/Validator/Validator_Web_API

Sarah
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 Topic: New branch created
rodrigue


Posts: 307
Location:
Cambridge UK
Registered:
February 2005
New branch created 20 Nov '09 08:17

Just to inform you that we created a new branch with marine to allow her
to work on the XML parser and the framework to support level 3.

Nico

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 Topic: (no subject)
Andreas Dräger


Posts: 273
Registered:
June 2006
(no subject) 23 Feb '10 10:50

Dear all,

We played around with the SBMLWriter class in JSBML and recognized
some problems when writing notes elements.

The SBML specification 2.4 says that one can add XHTML formatted notes
in two ways. First, each element can get the in-fix "xhtml:" within
the regular HTML tag. Second, the body element may declare the XHTML
name space.

In our test, only the second form worked. Furthermore, it is a bit
unhandy if the user is required to declare the body tag. I think it
would be very convenient to check the notes for "<xhtml:" or
"</xhtml:" pre-fixes and to set the body tag as required if this is
missing.

Finally, we recognized several problems with Annotation. It is not
possible to add CVTerms without explicitly creating an Annotation
object first. To this end, we created a dummy Annotation by calling
the constructor with an empty String and then we HAD to call the
method setAbout("") for this Annotation object. Without an explicit
call of setAbout, even with an empty String, the Writer always crashed
with a NullPointerException because there is a call of getAbout()
somewhere. In my opinion, the user of JSBML shouldn't have to care
about whether or not there is already an Annotation object because the
first time, any annotation element is added, an Annotation object
should be initialized. With this trick we were able to write SBML into
a file. However, the result was that the file contained many tags such
as <none>...</none>. Maybe the result of our call to setAbout(""). In
libSBML it was not necessary to set an about element. However, I
cannot find any occurence of "<none>" in any JSBML class.

And, what confuses people when using JSBML are constructors and
model.create*() methods that do not require arguments that are
actually obligatory. For instance, it is possible to create a
Compartment without setting an ID. This leads to errors in places
where people don't expect that the missing ID is actually the reason.
What happens is, that for instance a species that refers to the
compartment without an ID causes a NullPointerException when trying to
getCompartmentInstance() because this calls getModel().getCompartment().

After writing SBML and removing the <none>...</none> elements, the
SBML validator still showed many errors, for instance, " the element
'species' is not part of the definition of SBML". The reason is that
the Writer does not insert <listOf*>... </listOf*> tags surrounding
compartments, species, etc. Furthermore, it writes "spatialDimension"
and forgets the plural "s". In case of our compartment, there was
neither a notes nor an annotation element. But still the writer
creates an opening and a closing compartment tag. The validator does
in this case, however, only accept a compartment element that ends
with "/>".
There are several other errors but I think this is enough for just one e-mail.

It would also be nice to indent the SBML output so that it becomes
better human-readable.

I think there is still a lot of work ahead of us ;-)

Cheers
Andreas

Dipl.-Bioinform. Andreas Dräger
Eberhard Karls University Tübingen
Center for Bioinformatics (ZBIT)
Sand 1
72076 Tübingen
Germany

Phone: +49-7071-29-70436
Fax: +49-7071-29-5091
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 Topic: Complete type hierarchy
Andreas Dräger


Posts: 273
Registered:
June 2006
Complete type hierarchy 20 Apr '10 17:14

Dear all,

it is not so easy to keep the overview, but I think the attached figure
really covers the complete type hierarchy. Last time I forgot to add the
arrow from MathContainer to AbstractSBase and also
ModifierSpeciesReference. Both is now included. Please also see
http://yuml.me/diagram/scruffy/class/[<<SBase>>]^-.-[<<NamedSBase>>],
[<<SBase>>]^-.-[<<SBaseWithDerivedUnit>>],
[<<SBaseWithDerivedUnit>>]^-.-[MathContainer],
[<<SBaseWithDerivedUnit>>]^-.-[Reaction],
[<<NamedSBase>>]^-.-[<<Quantity>>],
[<<SBaseWithDerivedUnit>>]^-.-[<<Quantity>>],
[MathContainer]^-[FunctionDefinition],
[<<NamedSBase>>]^-.-[FunctionDefinition], [MathContainer]^-[KineticLaw],
[<<SBase>>]^-.-[AbstractSBase], [AbstractSBase]^-[AbstractNamedSBase],
[<<NamedSBase>>]^-.-[AbstractNamedSBase],
[AbstractNamedSBase]^-[Reaction], [AbstractSBase]^-[ListOf],
[AbstractSBase]^-[SBMLDocument], [AbstractSBase]^-[Unit],
[AbstractSBase]^-[MathContainer], [MathContainer]^-[Constraint],
[MathContainer]^-[Delay], [MathContainer]^-[EventAssignment],
[MathContainer]^-[InitialAssignment], [MathContainer]^-[KineticLaw],
[MathContainer]^-[Rule], [MathContainer]^-[StoichiometryMath],
[MathContainer]^-[Trigger], [Rule]^-[AlgebraicRule],
[Rule]^-[AssignmentRule], [Rule]^-[RateRule],
[AbstractNamedSBase]^-[CompartmentType], [AbstractNamedSBase]^-[Event],
[AbstractNamedSBase]^-[Model],
[AbstractNamedSBase]^-[SimpleSpeciesReference],
[AbstractNamedSBase]^-[SpeciesType],
[AbstractNamedSBase]^-[UnitDefinition],
[SimpleSpeciesReference]^-[SpeciesReference],
[SimpleSpeciesReference]^-[ModifierSpeciesReference],
[<<Quantity>>]^-.-[QuantityWithDefinedUnit],
[<<Quantity>>]^-.-[<<Variable>>], [<<Variable>>]^-.-[Symbol],
[QuantityWithDefinedUnit]^-[Symbol], [Symbol]^-[Compartment],
[Symbol]^-[Species], [Symbol]^-[Parameter],
[<<Variable>>]^-.-[SpeciesReference],
[QuantityWithDefinedUnit]^-[LocalParameter],
[AbstractNamedSBase]^-[QuantityWithDefinedUnit].

Cheers
Andreas

--
Dipl.-Bioinform. Andreas Dräger
Eberhard Karls University Tübingen
Center for Bioinformatics (ZBIT)
Sand 1
72076 Tübingen
Germany

Phone: +49-7071-29-70436
Fax: +49-7071-29-5091

      
 Topic: MathMLParser
Andreas Dräger


Posts: 273
Registered:
June 2006
MathMLParser 13 May '10 21:58

Dear all,

Currently, I am looking at the writing methods of JSBML. There I noticed
that currently, JSBML does not produce a nice indent as it is done in
libSBML. I just play around a little bit and try to improve this. Maybe
you have some idea about how to solve this?

Another question to this is, that Level and Version of An SBML document
can be undefined. What will happen in this case? Will we simply create
invalid SBML files? From my perspective, it would be much better to
throw an exception in such a situation. Otherwise users will have the
impression, everything is correct but then they will not be able to work
with their files.

The last thing I would like to mention is about the MathMLParser. I know
that it is not yet implemented. But, I would like to draw your attention
to the interface ASTNodeCompiler. This has already been implemented for
the TextEquation and also LaTeX export (both has to be improved but
should at least run). The ASTNodeCompiler recursively evaluates the
content of an abstract syntax tree. The same thing is necessary when
writing its content to an SBML file. Actually, what we simply have to do
is to implement the interface ASTNodeCompiler also for MathML export.
Should the class MathMLParser implement this interface? Or should we
implement another class for this purpose that is used by MathMLParser?

I am writing this e-mail just to make sure everybody knows about the
ASTNodeCompiler and to avoid that the same recursive function will be
implemented again.

Cheers
Andreas

--
Dipl.-Bioinform. Andreas Dräger
Eberhard Karls University Tübingen
Center for Bioinformatics (ZBIT)
Sand 1
72076 Tübingen
Germany

Phone: +49-7071-29-70436
Fax: +49-7071-29-5091
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 Topic: initDefaults
Andreas Dräger


Posts: 273
Registered:
June 2006
initDefaults 10 Aug '10 06:23

-----BEGIN PGP SIGNED MESSAGE-----
Hash: SHA1

Dear all,

I just noticed that we have different opinions about what the method
initDefaults() in some classes should do. My opinion is that it always
knows what to do depending on the level and version properties. If, for
instance, neither level nor version are set, initDefaults will perform
the correct operations to set some elements to null and some isSet*
fields to false. If, however, level and/or version are set,
initDefaults() will also know how to initialize all fields of the
respective element for the given L/V combination.

In case of reactions I noticed that suddenly the empty constructor does
not call the initDefaults() method anymore, irrespective of that we
already agreed that ListOf* objects should always be initialized to
avoid the following source of unnecessary NullPointerExceptions:

Reaction r = new Reaction();
r.getListOfModifiers().size();

will throw a NullPointerException instead of returning 0.

InitDefaults() should be used to decide what to do if neither level nor
version is set. Instead of the current implementation

public void initDefaults() {
if (isSetLevel() && isSetVersion()) {

if (level < 3) {
reversible = new Boolean(true);
fast = new Boolean(false);
} else {
reversible = fast = null;
}
initReactantList();
initProductList();
initModifierList();
}
}

it should read


public void initDefaults() {
initReactantList();
initProductList();
initModifierList();
if (isSetLevel() && isSetVersion()) {
if (level < 3) {
reversible = new Boolean(true);
fast = new Boolean(false);
} else {
reversible = fast = null;
}
} else {
reversible = fast = null;
isSetReversible = isSetFast = false;
}
}

It should be totally secure to always call initDefaults(), which will
reset the object to the correct values for the given L/V combination. It
is particularly important to have this method because we have so many
differen constructors and can sometimes not call one constructor from
another one.

For instance,

public Reaction(int level, int version) {
super(level, version);
initDefaults();
}

and

public Reaction() {
super();
// Cannot call initDefaults() until the level and version is set
// initDefaults();
}

- -> Actually, the first constructor should call the second one before
calling the super constructor, but we cannot do this. Hence, we need
initDefaults to initialize all objects.

Cheers
Andreas

- --
Dipl.-Bioinform. Andreas Dräger
Eberhard Karls University Tübingen
Center for Bioinformatics (ZBIT)
Sand 1
72076 Tübingen
Germany

Phone: +49-7071-29-70436
Fax: +49-7071-29-5091
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 Topic: Survey for selecting JSBML logo
Mike Hucka


Posts: 961
Registered:
October 2003
Survey for selecting JSBML logo 17 Sep '10 08:37

Hello SBML enthusiasts and developers,

The JSBML project has been trying to choose a logo. It is
time to get more opinions and put things to a vote. Here's
a survey for this purpose:

http://www.surveymonkey.com/s/choosing-jsbml-logo

The deadline is midnight, Sep. 22 (in your timezone).

Please help the project by rating the different logo
options. You can give them values from 1 to 10, with 10
being the highest/best score. You do not have to rate every
one, and you do not have to use a rating only once. (So,
for example, if you like 2 choices equally, you can give
them the same rating.)

The winning logo will be the one that gets the highest mean
rating from among all the votes cast.

Thanks for your help,
MH (on behalf of JSBML)
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 Topic: Yet another abstract super class
Andreas Dräger


Posts: 273
Registered:
June 2006
Yet another abstract super class 21 Oct '10 03:20

Dear all,

When starting the JSBML project it was one of our goals to introduce
common super types whenever elements share some common properties. Just
now we noticed that InitialAssignment, EventAssignment, and ExplicitRule
share a pointer to some variable field. I would therefore like to
introduce a new abstract data type Assignment as super type for all
these elements. However, as ExplicitRule has already an abstract class
as super type, the class Rule should become an interface. To make sure,
Rule is a MathContainer, we should therefore also introduce a new
abstract class AbstractMathContainer and change MathContainer to an
interface as the supertype of Rule. Assignment would then also extend
AbstractMathContainer and would serve as super type for all those
elements that assign the result of a mathematical expression to some
variable. What do you think?

Cheers
Andreas

--
Dipl.-Bioinform. Andreas Dräger
Eberhard Karls University Tübingen
Center for Bioinformatics (ZBIT)
Sand 1
72076 Tübingen
Germany

Phone: +49-7071-29-70436
Fax: +49-7071-29-5091
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 Topic: Re: problem loading SBML input with current version from trunk
rodrigue


Posts: 307
Location:
Cambridge UK
Registered:
February 2005
Re: problem loading SBML input with current version from trunk 15 Nov '10 04:51

Hi Paulo,

On 11/12/2010 04:54 PM, Paulo Maia wrote:
> Hi Nicolas,
>
> I was unsure wether to submit a bug report for this or not...
>
> I was trying to create an SBML loader for OptFlux using your current
> implementation of JSBML since, to my knowledge, MathML support is now
> available.
>
Yes, it is.

> The problem I'm having is still before the actual xml parsing begins:
>
> Exception in thread "main" java.lang.NullPointerException
> at java.util.Properties.loadFromXML(Properties.java:851)
> at
> org.sbml.jsbml.xml.stax.SBMLReader.initializePackageParserNamespaces(SBMLReader.java:242)
> at
> org.sbml.jsbml.xml.stax.SBMLReader.getInitializedPackageParsers(SBMLReader.java:145)
> at
> org.sbml.jsbml.xml.stax.SBMLReader.readSBMLFromStream(SBMLReader.java:412)
> at org.sbml.jsbml.xml.stax.SBMLReader.readSBML(SBMLReader.java:329)
> at org.sbml.jsbml.xml.stax.SBMLReader.readSBMLFile(SBMLReader.java:358)
> at org.sbml.jsbml.xml.stax.SBMLReader.readSBML(SBMLReader.java:343)
> at org.sbml.jsbml.JSBML.readSBMLFromFile(JSBML.java:265)
> at
> metabolic.io.readers.OptFluxJSBMLReader.getContainer(OptFluxJSBMLReader.java:51)
> at test.OptFluxJSBMLReaderTest.main(OptFluxJSBMLReaderTest.java:16)
>
>
> When analyzing the code, I found out that the
> org.sbml.jsbml.xml.stax.SBMLReader.initializePackageParserNamespaces
> method was trying to access a
> "org/sbml/jsbml/resources/cfg/PackageParserNamespaces.xml file. This
> file does not exist in that location and the process dies immediately
> with the a nullpointer exception...
>
> public static void initializePackageParserNamespaces() {
> Properties p = new Properties();
> try {
> p.loadFromXML(Resource.getInstance()
> .getStreamFromResourceLocation("org/sbml/jsbml/resources/cfg/PackageParserNamespaces.xml"));
>
>
> I am not sure if am using the correct method to load the SBML file,
> thus this e-mail... I am using the JSBML.readSBMLFromFile() method to
> give me the SBMLDocument instance...
>
> Is this correct or am I missing something?
>
Do you used ant to create the jsbml jar file ? Or are you trying to run
it directly from a JDE ?

The problem is that you probably did not add the resources folder to
your CLASSPATH, this is there that the different configuration files are.
I guess this is one more point that we need to add in our future
documentation.

Let me know if it solve your problem,
Thanks,
Nico





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 Topic: org.sbml.jsbml.xml.stax.SBMLReader
rodrigue


Posts: 307
Location:
Cambridge UK
Registered:
February 2005
org.sbml.jsbml.xml.stax.SBMLReader 18 Nov '10 08:06

Hi,

Can I ask people not to make any changes to the SBMLReader ?
I will restructure it as the readSBMLFromStream is a bit too long and
try to modify it to allow to keep whitespace when reading the notes.
As I will change the structure of the class, it will be a pain
(probably) to merge the changes.

Thanks,
Nico
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