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Posts: 1
Registered: October 2004
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DOTcvpSB toolbox for optimization in systems biology
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09 Sep '09 04:34
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We are pleased to announce DOTcvpSB, a Matlab toolbox
for advanced optimization in systems biology.
Software and documentation available at:
http://www.iim.csic.es/~dotcvpsb/
DOTcvpSB facilitates the statement and solution of
dyamic optimization (optimal control) problems related
with biological systems, modelled with ODEs (although
arbitrary black-box models can be handled as well).
The toolbox can import SBML models for the dynamics via
the SBMLtoolbox.
Examples of problems provided with the toolbox:
- optimal drug infusion to a patient
- minimization of intracellular oscillations
- bioreactor optimization
DOTcvpSB is described in the following paper:
Hirmajer, T., E. Balsa-Canto and J. R. Banga (2009)
DOTcvpSB, a software toolbox for dynamic optimization
in systems biology. BMC Bioinformatics 2009, 10:199.
http://www.biomedcentral.com/1471-2105/10/199/abstract/
More details, documentation and examples available at:
http://www.iim.csic.es/~dotcvpsb/
Regards,
Julio R. Banga ( julio@iim.csic.es )
Julio R. Banga
http://www.iim.csic.es/~julio/
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