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Dear Celine,

If you can define the value of u over time with some fitting procedure, a
simple way is to create a variable u and to fix its value with an
assignmentRule. You can use the SBML csymbol "time" to represent the
simulation time.

You can then use the symbol in another rateRule or a kineticLaw to determine x.

On 15/04/11 01:44, celine wrote:
>
> Hello!
>
> I'm trying to build a model to include a numerical data input... I'm pretty sure I'm doing a horrible job asking the question (which is why the search doesn't really help me much), so maybe I could give an example:
>
> Let us have 1 compartment where the rate of change is:
> dx/dt = x + u
> U would be our numerical data, and it is an experimentally measured quantity, which changes as time goes on (and we know the value as it changes, at least for some t)
>
> I could fit the data (U) with some splines in MATLAB, etc, if need be (and get more "data").
>
> What's the best way to get this into my SBML model?
>
> Thanks as always for all your help =)
> Celine
>
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--
Nicolas LE NOVERE, Computational Systems Neurobiology, EMBL-EBI, WTGC,
Hinxton CB101SD UK, Mob:+447833147074, Tel:+441223494521 Fax:468,
Skype:n.lenovere, AIM:nlenovere, twitter:@lenovere
http://www.ebi.ac.uk/~lenov/, http://www.ebi.ac.uk/compneur/

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