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Not all models are about elementary reactions :-).
Composite reactions can result in non-integer
stoichiometries.

You may then ask, why not multiply out common denominators
and generate integer stoichiometries? This was a topic of
some discussion at the SBML Forum meeting in Ft. Lauderdale.
The conclusion was that the resulting numbers don't
necessarily mean the same thing, qualitatively.

MH

--
Mike Hucka, Ph.D. mhucka@caltech.edu
Senior Research Fellow
Control and Dynamical Systems 107-81 tel: +1.626.395.6911
Caltech, Pasadena, CA 91125, USA fax: +1.702.554.3067