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Hi,

On 09-Dec-2002 Andrew Finney wrote:
>>parameter sets only
>>exist in the context of a model.

I aggree to this, but...

> however this doesn't mean that more than one set of
> parameters is meaningful for the same model. In fact
> this becomes a very meaningful way to represent mutants.
>
> An additional application (which might be close to Pedro's heart)
> is using parameter sets to store the results of different
> parameter optimisation/fitting runs on the same model.

Especially for this it becomes meaningful, because for fitting
you often use different experimental results, perturbing the
model and the cells with different conditions and initial values.
(feeding conditions, mutants with switched off pathways etc.)
All this parameters can be applied to _a family of models_
(model variants e.g. for hypothesis test).

Martin

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