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Posts: 469
Registered:
October 2003
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Re: Rate Law Problem
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20 Apr '06 03:21
 
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> Still feel confusing here. Do you mean I dissociate the reaction into the following two reactions?
> PyrI <-> PyrM
> HM <-> HI
> The reaction mechanism of the origianl reaction is Rapid Equilibrium Random Bi Bi, so the rate equation is a function of PyrI, PyrM, HM, HI and E. After the dissociation, how to use the rate equation then?
This is not an SBML problem, but a modelling problem. How did-you want
to write the rate-equation? How did-you intend to take into account
the different volumes of the two compartments?
One possibility I encountered is actually to model only one
compartment and to use a corrective factor in the rate-law for the
adequate species that represent the ratio of the size of the real
compartments.
--
Nicolas LE NOVERE, Computational Neurobiology,
EMBL-EBI, Wellcome-Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
Tel: +44(0)1223 494 521, Fax: +44(0)1223 494 468, Mob: +33(0)689218676
http://www.ebi.ac.uk/~lenov AIM screen name: nlenovere
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