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Nicolas Le Novere


Posts: 469
Registered:
October 2003
RE: Suggestion for new section in SBML 11 Feb '06 17:14 Go to previous messageGo to previous message


> Membrane potential (Vm). Clearly can be expected to change with time, but
> just as clearly is not a Species. Some models obtain Vm by keeping track
> of
> the charge on the membrane capacitance. This is then an algebraic rule
> giving Vm = Q/C and the variation in time arises because the charged
> species that make up Q are changing. In this case no initial condition is
> required since the initial value of Vm is determined by the initial values
> of the charged species. Other models write dVm/dt = i/C and the time
> dependence arises from changing membrane currents that make up the total
> current, i. In either case Vm is time varying, but in neither case is it
> obvious to me how to encode it in SBML.

It is encoded as a rate-rule in the Hodgkin-Huxley we have in BioModels DB
(It originally comes form CellML repository I think)

http://www.ebi.ac.uk/compneur-srv/biomodels-main/publ-model.do?mid=BIOMD0000000020

--
Nicolas LE NOVÈRE, Computational Neurobiology,
EMBL-EBI, Wellcome-Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
Tel: +44(0)1223 494 521, Fax: +44(0)1223 494 468, Mob: +33(0)689218676
http://www.ebi.ac.uk/~lenov


      

SubjectPosterDate
Read Message   Suggestion for new section in SBML Herbert Sauro09 Feb '06 23:51
Read Message   Re: Suggestion for new section in SBML Rainer Machne10 Feb '06 04:46
Read Message   Re: Suggestion for new section in SBML Martin Ginkel10 Feb '06 04:51
Read Message   RE: Suggestion for new section in SBML rphair10 Feb '06 12:31
Read Message   RE: Suggestion for new section in SBML  Nicolas Le Novere11 Feb '06 17:14
Read Message   Re: Suggestion for new section in SBML Jordan Atlas11 Feb '06 11:37
Read Message   Re: Re: Suggestion for new section in SBML Martin Ginkel13 Feb '06 00:39
Read Message   Re: Re: Suggestion for new section in SBML Mike Hucka14 Feb '06 19:31
Read Message   Re: Re: Suggestion for new section in SBML Martin Ginkel15 Feb '06 02:10
Read Message   Re: Re: Suggestion for new section in SBML Mike Hucka15 Feb '06 10:58
Read Message   Re: [sbml-discuss]Suggestion for new section in SB... Martin Ginkel15 Feb '06 23:51
Read Message   Re: Suggestion for new section in SBML bshapiro11 Feb '06 19:52
Read Message   Re: Suggestion for new section in SBML Mike Hucka14 Feb '06 19:23
Read Message   RE: Suggestion for new section in SBML Andrew Finney17 Feb '06 00:53
Read Message   RE: Suggestion for new section in SBML Nicolas Le Novere19 Feb '06 11:05
Read Message   RE: Suggestion for new section in SBML Andrew Finney19 Feb '06 13:49
Read Message   RE: Suggestion for new section in SBML Nicolas Le Novere19 Feb '06 16:05
Read Message   RE: Suggestion for new section in SBML Herbert Sauro20 Feb '06 12:57
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