RE: Multiple kineticLaw Sections Per Reaction
11 Mar '06 15:23
> It would allow the reactions, for the stochastic simulators among us, to
> be specified in a more logical manner, and presumably, it would allow for
> elementary mode analysis to perform better when reactions are specified as
> actually being reversible instead of two irreversible reactions (I
> assume-- I'm not familiar with elementary mode analysis).
But .... any reversible reaction IS in fact the sum of two irreversible
You mentioned stochastic simulations. But you are only talking about
population-based stochastic simulations. If you use particle-based
approaches, the on and off reactions are obligatory uncoupled. The
reversibility is only an averaged phenotype of the whole populations.
> Finally, it
> would allow graphics packages to easily and correctly recognise and
> display reversible reactions.
Well, if I have two reactions A->B and B->A with the same modifier(s), the
reconstruction is not hugely difficult.
Nicolas LE NOVÈRE, Computational Neurobiology,
EMBL-EBI, Wellcome-Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
Tel: +44(0)1223 494 521, Fax: +44(0)1223 494 468, Mob: +33(0)689218676