About

Contents

SBML is the result of many people's efforts over many years. This page lists individuals and groups who have (or have had) specific roles, but this short list is not meant to diminish the contributions of the broader community of people and companies developing software systems that use SBML.

People's involvements also change over time, and we try to keep this page updated to stay current with the SBML community.

The SBML Editors and the Chair

The SBML Editors are devoted experts who write official specification documents, correct errata, assess proposals, and manage revisions to SBML. They are elected by the SBML community and serve for 3-year terms as volunteers. There are five Editors plus one Chair. The Chair is the leader of the SBML Team (described below), and acts as overall coordinator.


Frank Bergmann

Frank Bergmann (M.S. in Computer Science) is pursuing a Ph.D. in Computational Systems Biology at Claremont Graduate University's Keck Graduate Institute. He is the lead software developer for the Systems Biology Workbench and his projects include roadRunner and Simulate3D.

(''Chair'') Michael Hucka

(Chair) Michael Hucka (Ph.D. in Computer Science and Engineering) is a Senior Research Fellow at Caltech. He has Chaired the SBML Editors and SBML Team by community consensus since 2003. Today he works on all aspects of SBML and is involved with BioModels.net consortium efforts such as BioModels Database.

Sven Sahle

Sven Sahle (Ph. D. in Theoretical Chemistry) is a junior group leader in the department for modeling of biological processes at the University of Heidelberg. He's one of the lead software engineers of COPASI. His interests include the dynamic properties of biochemical models.

James C. Schaff

James C. Schaff (B.S. in Computer Science and Engineering) is an assistant professor at Center for Cell Analysis and Modeling at the U. Connecticut Health Center. He is Lead Developer of the Virtual Cell and is interested in abstractions, formalisms and numerical methods in biological modeling.

Lucian Smith

Lucian Smith (Ph.D. in Biochemistry) is a Research Consultant in the Bioengineering Department at the University of Washington. He works in the Sauro lab, and is the lead developer of Antimony. His interests include modularity of modeling languages and applying modeling to synthetic biology. He has also worked on phylogeny software.

Darren J. Wilkinson

Darren J. Wilkinson (Ph.D. in Bayesian statistics) is Professor of Stochastic Modelling in the School of Stochastic Modelling at the University of Newcastle Upon Tyne, UK. He is involved in a variety of systems biology projects at Newcastle, including the Centre for Integrated Systems Biology of Ageing and Nutrition (CISBAN).


Past SBML Editors have been Sarah M. Keating (2007–2009), Stefan Hoops (2007–2009), Nicolas Le Novère (2006–2008), Andrew M. Finney (2000–2006), Herbert M. Sauro (2000–2006), and Hamid Bolouri (2000–2006). The SBML effort and community benefitted tremendously from their involvement and hard work.

The SBML Partners

SBML is a decentralized community effort that began in John Doyle's group at Caltech, with Hamid Bolouri, Andrew Finney, Herbert Sauro and Michael Hucka. Over the years, a few groups have devoted large portions of their resources, time, and energy, over many years, to support SBML in all ways, in particular by obtaining independent funding for explicit SBML development and hosting members of the SBML Team (described below). The SBML Partners are, in effect, the backbone of the SBML effort.


Hucka Group
California Institute of Technology
Pasadena, California
US


Le Novère Group
European Bioinformatics Institute
Wellcome Trust Genome Campus, Cambrige
UK

Past SBML Partners have been the Kitano group at the Systems Biology Institute (Japan), the Bolouri group at the University of Hertfordshire (UK), and the Brent group at the Molecular Sciences Institute (US). The Hucka group at Caltech is a subgroup of the Doyle group.

The SBML Team

The SBML Team strives to support the SBML community and the development and maintenance of specific SBML infrastructure and facilities. In particular, the team is responsible for (1) maintaining this website, the SBML mailing lists, electronic surveys, and other resources; (2) arranging for the development and support of critical software, including libSBML, the SBML Validator, and the SBML Test Suite; and (3) organizing SBML events, including the SBML Forum Meetings and SBML Hackathons.


Michael Hucka

Michael Hucka is the current SBML Team leader, a role he has performed together with being the Chair of the SBML Editors since 2003. He works on all aspects of SBML development, as well as contributing to libSBML and other software efforts, writing grants, organizing workshops, maintaining the SBML.org website and back-end servers, and other odd jobs.

Sarah M. Keating

Sarah M. Keating is the current lead developer for libSBML and the SBMLToolbox. She is also developing the SBML Test Suite and the upcoming new SBML Reference Implementation project.

Bruce E. Shapiro

Bruce E. Shapiro (Ph.D. in Biomathematics) is the co-director of the BNMC with Mike. Bruce developed MathSBML and Cellerator, and is involved in many other activities. His current interests include computational morphodynamics, computational neuroscience, and modeling of signal transduction networks.

Akiya Jouraku

Akiya Jouraku (Ph.D. in Computer Science) is a Research Assistant in the Dept. of Biosciences and Informatics at Keio University, Japan. He is a developer of libSBML, CellDesigner and KEGG2SBML. His current research interests include systems biology, interconnection networks, and parallel processing.

Linda Taddeo

Linda Taddeo (M.S. in Applied Computer Science and Technology) provides administrative support related to SBML activities, including travel and workshop organization. She also aids in the maintenance of the SBML website, in managing financial arrangements and other activities as needed.


Past Members of the SBML Team

The SBML effort has greatly benefitted from the involvement of many talented individuals over the years. Some are still active in SBML; others have moved on to other exciting work.

  • Hamid Bolouri was the leader of the Caltech SBML & SBW Team from 1999 until 2003, as well as the University of Hertfordshire SBML Team for several years. In addition to Hamid's roles in the initial development of SBML, his group developed several SBML-related software resources (including the first SBML model repository and online SBML validator), and was the alma mater of Maria Schilstra, Sarah Keating, Joanne Matthews, and others. He continues to perform research in systems biology, and recently published two new books (Computational Modeling of Gene Regulatory Networks—A Primer and Personal Genomics and Personalized Medicine).
  • Andrew M. Finney was a member of the SBML Team from the very beginning. Until his return to industry, he was one of SBML's chief architects and greatest contributors.
  • Herbert M. Sauro was another original member of the SBML Team and the implementor of the earliest SBML-aware simulation software, Jarnac and JDesigner. He is now faculty at the University of Washington.
  • Maria J. Schilstra developed the original CellML2SBML and the first NetBuilder, the latter being one of the first applications to understand SBML when SBML was first introduced. Maria also created the first SBML model repository, the contents of which seeded the very first instantiation of BioModels Database. She has also made many other contributions to SBML over the years. Maria is currently the group leader of the Biological and Neural Computation Laboratory at the University of Hertfordshire, UK.
  • Ben Bornstein is a software engineer at the NASA Jet Propulsion Laboratory. He is the architect of libSBML and for a long time was its primary developer; he also developed the second generation of the SBML online validator.
  • Akira Funahashi, Ph.D. in Computer Science, co-developed KEGG2SBML and CellDesigner (née SBEdit), as well as contributed to libSBML, and has been involved with such things as SBGN from the very beginning. At the beginning of the SBML project, Akira was a researcher in the Kitano Symbiotic Systems Project and The SBI. Today he is an Associate Professor in the Dept. of Biosciences and Informatics at Keio University.
  • Ben Kovitz is a freelance software engineer who worked on many things in SBML and SBW, including having written the wiki engine that ran the sbml.org website from 2002 to 2008, parts of libSBML, and RFC 3823 defining the MIME type for SBML. He is now pursuing a Ph.D. at Indiana University.
  • Joanne Matthews was a research programmer at the University of Hertfordshire, UK, in Maria Schilstra's group. Among other things, she worked on CellML2SBML as well as the first generation of the SBML.org online tools.
  • Enuo He was a visiting student in the BNMC during 2007. She worked on both developing test cases for the SBML Test Suite and on curating models for BioModels Database. She is now at the University of Oxford pursuing her Ph.D.
  • Kimberly Begley worked as a consultant during 2008 on the SBML Test Suite. She has degrees in both Computer Science and Biology and is a Bioinformatics Consultant working in Australia. She has over a decade of experience developing database and XML systems for groups including QFAB, MDS Proteomics, Blueprint, and Lilly Systems Biology.

SBML Contributors

Development of SBML specifications is open and proceeds with input from the user community. Many people have spent significant time developing proposals for SBML enhancements and extensions. The following is an attempt to credit everyone who has developed written proposals for SBML changes (other than those by the original SBML Team). We greatly appreciate notices of omissions and other errors (please email sbml-team@caltech.edu) so that we can make this list as accurate as possible.

Person(s) Group Topic First publicized
Daniel Lucio,
James Schaff,
John Wagner
Virtual Cell Team,
Univ. of Connecticut Health Center, USA
Representing spatial geometry Jun. '01 (3rd Forum)
Eric Mjolsness,
Bruce Shapiro
Machine Learning Systems
NASA Jet Propulsion Lab, USA
Support for arrays Jun. '01 (3rd Forum)
Martin Ginkel,
Jörg Stelling
Gilles group
MPI Magdeburg, Germany
Modularity of models Jun. '01 (3rd Forum)
Nicolas Le Novère
Tom Shimizu
Bray Group
University of Cambridge, UK
Multistate molecules & complex species Jun. '01 (3rd Forum)
Igor Goryanin,
Hugh Spence
GlaxoSmithKline
UK
Miscellaneous SBML extensions proposal Jun. '01 (3rd Forum)
Naoki Tanimura,
Maki Nakayama,
Yuichiro Inagaki,
Takayuki Saito,
Akira Funahashi
Systems Biology Institute
Japan
Representation of graphical diagrams Jul. '02 (5th Forum)
Sven Sahle,
Ralph Gauges,
Ursula Rost,
Katja Wegner
EML Research gGmbH
Germany
Diagram layout Nov. '03 (8th Forum)
Claudine Chaouiya,
Elisabeth Remy,
Denis Thieffry
LGPD/IBDM/IML
France
Logical regulatory networks Oct. '04 (9th Forum)
Michael Blinov T-10 group
Los Alamos National Laboratory, USA
Rule-based models Oct. '04 (9th Forum)
Colin Gillespie,
Darren Wilkinson,
Richard Boys,
Carole Proctor,
Daryl Shanley,
Tom Kirkwood
BASIS Group
Newcastle University, UK
Distributions May '05 (sbml-discuss)
Frank Bergmann Sauro Group
Keck Graduate Institute, USA
Render extension Oct. '05 (10th Forum)
Karthik Raman Indian Institute of Science
India
Flux balance models Oct. '06 (11th Forum)
Ranjit Randhawa,
Cliff Shaffer
JigCell Group
Virginia Tech, USA
Model composition Mar. '06 (ICSB 2006)
Stefan Hoops COPASI Team,
Virginia Bioinformatics Institute, USA
Hierarchical model composition Oct. '07 (12th Forum)
Anika Oellrich,
Nicolas Le Novère
Comp. Neuroscience Group
EMBL-EBI, UK
Multicomponent & multistate species Oct. '08 (13th Forum)
Duncan Berenguier,
Nicolas Le Novère
Comp. Neuroscience Group
EMBL-EBI, UK
Qualitative models Oct. '08 (13th Forum)
Frank Bergmann,
Brett Olivier
Univ. of Washington and VU University Amsterdam
USA and The Netherlands
Flux Balance Oct. '09

Funding

We are grateful for the funding agencies and organizations that have supported SBML in the past and continue to support it today. Without them, SBML would not exist. Our acknowledgments page provides a full list of who they are.

The principal investigator on the project that lead to the development of the first specification of SBML was Hiroaki Kitano, and the PI of the subcontract to Caltech was John C. Doyle. In addition to the JST-funded project, Hiroaki Kitano, John C. Doyle, Hamid Bolouri, and Roger Brent at different times obtained funding from various agencies in the USA, Japan and UK to support staff and meetings aimed at continuing the development of SBML and associated resources. Since 2005, other principal investigators (notably Michael Hucka at Caltech) have obtained funding to continue development and support of SBML.

Ownership

No one—not the principal investigators, nor the SBML Editors, nor the SBML Team, nor the funding agencies or anyone else—owns SBML; it is a free and open community effort that extends beyond any single group, and we view ourselves only as organizers and fellow developers.


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