This is an XML file, and will not display properly in most browsers. To view the entire file use the "View Source" or "Save File" option on your browser.

A Simple Mitotic Oscillator. Reference:Goldbeter A (1991)A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase, PNAS 88:9107-9111

In addition, this model includes a variable Mass, which splits in half when the variable M passes a threshold.

The purpose of this model is to demonstrate an SBML model that contains all of the following: a rate rule, an algebraic rule, an assignment rule, one-sided reactions, two-sided reactions, modifiers, differential-algebraic equations, a function, and an event

m mpf m 0.6 mpf 0.7

Mass mu

C VM1 C Kc -1

M VM3 -1 V3

vi -1 C kd

C vd X C Kd -1

MI V1 K1 MI -1

M V2 K2 M -1

V3 XI K3 XI -1

V4 X K4 X -1

mitosis Mass M

Mass 2 -1